CBS still has yet to announce whether "Coyote" will be renewed for a second season. Since the premiere of Season 1, star Michael Chiklis posted a tweet on March 13, 2021, saying he "Can't wait to get back to work" on "Coyote." That doesn't indicate whether "Coyote" is coming back, but it also doesn't mean it's canceled, either.
"Coyote" would seem to have a better shot at renewal than the average TV show, however. It was one of the flagship shows on the rebranded Paramount+ network. "Coyote" was originally planned for the Paramount Network, but in November 2020, CBS moved the series to CBS All Access, its subscription-based streaming platform (via The Wrap). CBS All Access was then rebranded as Paramount+ on March 4, 2020.
If "Coyote" does return, Chiklis will presumably be back as former border patrol agent Ben Clemens, as the show doesn't really exist without him. Some of the primary villains may also be back, including cartel leader Juan Diego "El Catrin" Zamora, who is played by Juan Pablo Raba. The plot, meanwhile, is likely to continue where the Season 1 cliffhanger left off. Previously, Ben's work with the Zamora cartel had attracted the attention of the CIA, and in the finale, he pitched himself as a confidential informant for the spy agency.